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Article

A machine learning model for the prediction of down syndrome in second trimester antenatal screening

15 Jul 2021

Abstract excerpt

BACKGROUND: Down syndrome (DS) is the most common human chromosomal abnormality. About 1200 laboratories carry out antenatal screening for DS in second trimester pregnancies in China. Their prenatal assessment of DS pregnancy risk is based on biometric calculations conducted on maternal serum biochemical markers and ultrasonic markers of fetal growth. However, the performance of this triple test for DS in second...

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Share to Down syndrome and intellectual disability research
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PMID: 34274342
DOI: 10.1016/j.cca.2021.07.015

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