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Article

B-chronic lymphocytic leukemia chemoresistance involves innate and acquired leukemic side population cells.

Leukemia - 1 Nov 2010

Gross E, L'Faqihi-Olive F-E, Ysebaert L, Brassac M, Struski S, Kheirallah S, Fournié J-J, Laurent G, Quillet-Mary A

Abstract excerpt

B-cell chronic lymphocytic leukemia (B-CLL) therapy remains unsatisfactory due to repeated resurgences of the chemoresistant disease. In this study, we investigated the basis of this chemoresistance by applying the 'side population' (SP) analysis to blood samples from B-CLL patients. We report the existence of few natural SP cells, which harbors phenotypic and cytogenetic hallmarks of B-CLL in most patients with...

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Identifiers

PMID: 20827287
DOI: 10.1038/leu.2010.176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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