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Article

Structural alterations in a component of cytochrome c oxidase and molecular evolution of pathogenic Neisseria in humans.

PLoS pathogens - 19 Aug 2010

Aspholm Marina, Aas Finn Erik, Harrison Odile B, Quinn Diana, Vik Ashild, Viburiene Raimonda, Tønjum Tone, Moir James, Maiden Martin C J, Koomey Michael

Abstract excerpt

Three closely related bacterial species within the genus Neisseria are of importance to human disease and health. Neisseria meningitidis is a major cause of meningitis, while Neisseria gonorrhoeae is the agent of the sexually transmitted disease gonorrhea and Neisseria lactamica is a common, harmless commensal of children. Comparative genomics have yet to yield clear insights into which factors dictate the unique...

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Identifiers

PMID: 20808844
DOI: 10.1371/journal.ppat.1001055
PMCID: PMC2924362

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