Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach

Abstract excerpt

BACKGROUND: The increased sequencing of pathogen genomes and the subsequent availability of genome-scale functional datasets are expected to guide the experimental work necessary for target-based drug discovery. However, a major bottleneck in this has been the difficulty of capturing and integrating relevant information in an easily accessible format for identifying and prioritizing potential targets. The...

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