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Article

Prioritizing Genomic Drug Targets in Pathogens: Application to Mycobacterium tuberculosis

5 Jun 2006

Abstract excerpt

We have developed a software program that weights and integrates specific properties on the genes in a pathogen so that they may be ranked as drug targets. We applied this software to produce three prioritized drug target lists for Mycobacterium tuberculosis, the causative agent of tuberculosis, a disease for which a new drug is desperately needed. Each list is based on an individual criterion. The first list...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16789813
DOI: 10.1371/journal.pcbi.0020061

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