Article
A set of genes associated with the interferon-γ response of lung cancer patients undergoing α-galactosylceramide-pulsed dendritic cell therapy.
Cancer science - 1 Nov 2010
Okita Kohsuke, Motohashi Shinichiro, Shinnakasu Ryo, Nagato Kaoru, Yamasaki Kazuki, Sato Yasunori, Kitamura Hiroshi, Hijikata Atsushi, Yamashita Masakatsu, Shimizu Kanako, Fujii Shin-Ichiro, Ohara Osamu, Taniguchi Masaru, Sakaida Isao, Nakayama Toshinori
Abstract excerpt
Invariant natural killer T (iNKT) cells possess potent antitumor effects after activation with a specific glycolipid antigen, α-galactosylceramide (αGalCer). A phase I-II clinical study of αGalCer-pulsed dendritic cells (DC) to activate endogenous iNKT cells was previously performed in patients w...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.