Article
Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics.
Molecular microbiology - 1 Oct 1990
Davis N K, Chater K F
Abstract excerpt
Streptomyces coelicolor produces spores whose development of a grey colour requires the activity of the whiE locus. The cloned whiE locus was identified after mobilization into a whiE mutant of a library of S. coelicolor DNA inserted into a transmissible plasmid vector. The whiE region of the cloned DNA was localized both by subcloning and by mutagenesis of the cloned DNA with the Streptomyces transposon Tn4560....
Topics
- Amino Acid Sequence
- Anti-Bacterial Agents
- Base Sequence
- Cloning, Molecular
- Codon
- DNA, Bacterial
- Furans
- Genes, Bacterial
- Lactones
- Molecular Sequence Data
- Mutation