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Article

Determinants of multidrug-resistant tuberculosis clusters, California, USA, 2004-2007.

Emerging infectious diseases - 1 Sept 2010

Metcalfe John Z, Kim Elizabeth Y, Lin S-Y Grace, Cattamanchi Adithya, Oh Peter, Flood Jennifer, Hopewell Philip C, Kato-Maeda Midori

Abstract excerpt

Laboratory and epidemiologic evidence suggests that pathogen-specific factors may affect multidrug-resistant (MDR) tuberculosis (TB) transmission and pathogenesis. To identify demographic and clinical characteristics of MDR TB case clustering and to estimate the effect of specific isoniazid resistance-conferring mutations and strain lineage on genotypic clustering, we conducted a population-based cohort study of...

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Identifiers

PMID: 20735924
DOI: 10.3201/eid1609.100253
PMCID: PMC3294976

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