Article
Designing logical rules to model the response of biomolecular networks with complex interactions: an application to cancer modeling.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Guziolowski Carito, Blachon Sylvain, Baumuratova Tatiana, Stoll Gautier, Radulescu Ovidiu, Siegel Anne
Abstract excerpt
We discuss the propagation of constraints in eukaryotic interaction networks in relation to model prediction and the identification of critical pathways. In order to cope with posttranslational interactions, we consider two types of nodes in the network, corresponding to proteins and to RNA. Micr...
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