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Article

Maternal and paternal lineage double heterozygosity alteration in familial breast cancer: a first case report.

Breast cancer research and treatment - 1 Dec 2010

Pilato Brunella, De Summa Simona, Danza Katia, Lambo Rossana, Paradiso Angelo, Tommasi Stefania

Abstract excerpt

Hereditary breast cancer syndrome was firstly associated with BRCA1 and BRCA2 genes the mutations of which confer high risk to develop breast and/or ovarian cancer. Double heterozygosity is a rare condition in which both BRCA1 and BRCA2 mutations are present in a family at the same time. In the c...

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Identifiers

PMID: 20730485
DOI: 10.1007/s10549-010-1125-3

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20730485-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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