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Article

The transgenerational impact of benzo(a)pyrene on murine male fertility

21 Aug 2010

Abstract excerpt

BACKGROUND: Benzo(a)pyrene (BaP) is an endocrine toxicant that is widely distributed in the environment. The adverse effects of BaP on fertility are well documented, however its effects on fertility in the subsequent generations are not known. We aimed to investigate the transgenerational effects of BaP on male fertility in mice. METHODS: Six-week-old male mice (F0) were orally administered BaP (1 or 10 mg/kg...

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PMID: 20729536
DOI: 10.1093/humrep/deq205

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