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Article

Intrachromosomal mitotic nonallelic homologous recombination is the major molecular mechanism underlying type-2 NF1 deletions.

Human mutation - 1 Oct 2010

Roehl Angelika C, Vogt Julia, Mussotter Tanja, Zickler Antje N, Spöti Helene, Högel Josef, Chuzhanova Nadia A, Wimmer Katharina, Kluwe Lan, Mautner Victor-Felix, Cooper David N, Kehrer-Sawatzki Hildegard

Abstract excerpt

Nonallelic homologous recombination (NAHR) is responsible for the recurrent rearrangements that give rise to genomic disorders. Although meiotic NAHR has been investigated in multiple contexts, much less is known about mitotic NAHR despite its importance for tumorigenesis. Because type-2 NF1 micr...

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Share to Chromosomes, Human, Pair 17
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20725927
DOI: 10.1002/humu.21340

Genes

SUZ12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20725927-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Intrachromosomal mitotic nonallelic homologous recombination is the major molecular mechanism underlying type-2 NF1 deletions.PMID 20725927Read ↗

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