Article
[Influence of CD14 gene polymorphism on the expression of high mobility group box-1 protein in patients with severe burn].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns - 1 Apr 2010
Dong Ning, Yao Yong-ming, Huang Xian-jin, He Li-xin, Yu Yan, Sheng Zhi-yong
Abstract excerpt
OBJECTIVE: To investigate the influence of the lipopolysaccharide receptor CD14-159C/T gene polymorphism on the synthesis and release of high mobility group box-1 protein (HMGB1), and its relation to sepsis in patients with severe burn. METHODS: Venous blood from 35 patients with burn area equal to or larger than 30% TBSA was obtained on post burn day (PBD) 1, 3, 5, 7, 14, 21, and 28 respectively. Eleven...
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