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Article

TARDBP gene mutations among Chinese patients with sporadic amyotrophic lateral sclerosis.

Neurobiology of aging - 1 May 2012

Huang Rui, Fang Deng-Fu, Ma Ming-Yi, Guo Xiao-Yan, Zhao Bi, Zeng Yan, Zhou Dong, Yang Yuan, Shang Hui-Fang

Abstract excerpt

Recently, several TARDBP mutations have been identified in sporadic amyotrophic lateral sclerosis (SALS) patients among different ethnicities. Our study aims to analyze the clinical features and mutations in the TARDBP gene among Chinese patients with SALS. One hundred sixty-five patients were studied. The mean age of onset was 50.8±12.0 years. The mean diagnostic delay was 18.8±17.1 months. A novel missense...

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Source

Identifiers

PMID: 20708823
DOI: 10.1016/j.neurobiolaging.2010.07.007

Genes

TARDBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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