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Article

Autophagy-dependent rhodopsin degradation prevents retinal degeneration in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Aug 2010

Midorikawa Ryosuke, Yamamoto-Hino Miki, Awano Wakae, Hinohara Yoshimi, Suzuki Emiko, Ueda Ryu, Goto Satoshi

Abstract excerpt

Recent studies have demonstrated protective roles for autophagy in various neurodegenerative disorders, including the polyglutamine diseases; however, the role of autophagy in retinal degeneration has remained unclear. Accumulation of activated rhodopsin in some Drosophila mutants leads to retinal degeneration, and although it is known that activated rhodopsin is degraded in endosomal pathways in normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20702701
DOI: 10.1523/JNEUROSCI.2061-10.2010
PMCID: PMC6634698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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