Article
Effect of neoadjuvant anthracycline-taxane-based chemotherapy in different biological breast cancer phenotypes: overall results from the GeparTrio study.
Breast cancer research and treatment - 1 Nov 2010
Huober Jens, von Minckwitz Gunter, Denkert Carsten, Tesch Hans, Weiss Erich, Zahm Dirk Michael, Belau Antje, Khandan Fariba, Hauschild Maik, Thomssen Christoph, Högel Bernhard, Darb-Esfahani Silvia, Mehta Keyur, Loibl Sibylle
Abstract excerpt
In order to explore the effect of neoadjuvant chemotherapy (NACT) on clinical mid-course and pathological complete response (pCR) at surgery in different biological breast cancer subtypes. The GeparTrio study included 2,072 patients with operable or locally advanced breast cancer. After two cycles with docetaxel, doxorubicin and cyclophosphamide (TAC) patients were randomized according to their clinical response....
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