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Article

Ancestral paternal genotype controls body weight and food intake for multiple generations.

Human molecular genetics - 1 Nov 2010

Yazbek Soha N, Spiezio Sabrina H, Nadeau Joseph H, Buchner David A

Abstract excerpt

Current treatments have largely failed to slow the rapidly increasing world-wide prevalence of obesity and its co-morbidities. Despite a strong genetic contribution to obesity (40-70%), only a small percentage of heritability is explained with current knowledge of monogenic abnormalities, common sequence variants and conventional modes of inheritance. Epigenetic effects are rarely tested in humans because of...

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Identifiers

PMID: 20696673
DOI: 10.1093/hmg/ddq332
PMCID: PMC2951864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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