Article
The XbaI G>T polymorphism of the glucose transporter 1 gene modulates 18F-FDG uptake and tumor aggressiveness in breast cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Aug 2010
Grabellus Florian, Sheu Sien-Yi, Bachmann Hagen S, Lehmann Nils, Otterbach Friedrich, Heusner Till A, Antoch Gerald, Bockisch Andreas, Kimmig Rainer, Schmid Kurt W, Stahl Alexander R
Abstract excerpt
UNLABELLED: We investigated the relevance of single-nucleotide polymorphisms (SNPs) in the glucose transporter 1 (GLUT1) gene to the uptake of (18)F-FDG and tumor aggressiveness in breast cancer. METHODS: In 52 individuals with breast cancer, a diagnostic PET/CT scan was obtained, and the standardized uptake value was determined as a measure of (18)F-FDG uptake using a region-of-interest technique. Three GLUT1...
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