Phagocytosis of<i>Cryptococcus neoformans</i>by, and Nonlytic Exocytosis from,<i>Acanthamoeba castellanii</i>

Abstract excerpt

Cryptococcus neoformans, an encapsulated, pathogenic yeast, is endowed with a variety of virulence factors, including a polysaccharide capsule. During mammalian infection, the outcome of the interaction between C. neoformans and macrophages is central to determining the fate of the host. Previous studies have shown similarities between the interaction of C. neoformans with macrophages and with amoebae, resulting...

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