Article
Characterization of SIV in the oral cavity and in vitro inhibition of SIV by rhesus macaque saliva.
AIDS research and human retroviruses - 1 Aug 2010
Thomas Jessica S, Lacour Nedra, Kozlowski Pamela A, Nelson Steve, Bagby Gregory J, Amedee Angela M
Abstract excerpt
Human immunodeficiency virus (HIV) infections are rarely acquired via an oral route in adults. Previous studies have shown that human whole saliva inhibits HIV infection in vitro, and multiple factors present in human saliva have been shown to contribute to this antiviral activity. Despite the widespread use of simian immunodeficiency virus (SIV)-infected rhesus macaques as models for HIV pathogenesis and...
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