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Article

Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactions

28 Jul 2010

Abstract excerpt

Monkeypox virus (MPV) is a zoonotic Orthopoxvirus and a potential biothreat agent that causes human disease with varying morbidity and mortality. Members of the Orthopoxvirus genus have been shown to suppress antiviral cell defenses, exploit host cell machinery, and delay infection-induced cell death. However, a comprehensive study of all host genes and virus-targeted host networks during infection is lacking. To...

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PMID: 20667104
DOI: 10.1186/1743-422x-7-173

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