Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Proteomic Strategy Reveal Combined α<sub>1</sub> Antitrypsin and Cathepsin D as Biomarkers for Colorectal Cancer Early Screening

14 Jul 2010

Abstract excerpt

Biomarkers for colorectal cancer (CRC) early diagnosis are currently lacking. The purpose of this study was to interpret molecular events in the early stage of CRC that may bring about new biomarkers for early diagnosis. Methylation isotope labeling assistant gel-enhanced liquid chromatography-mass spectrometry (GeLC-MS) strategy was developed to improve protein identification in quantitative proteome analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to Protease and Inhibitor Mechanisms
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20666480
DOI: 10.1021/pr100406z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Proteomic Strategy Reveal Combined α<sub>1</sub> Antitrypsin and Cathepsin D as Biomarkers for Colorectal Cancer Early ScreeningPMID 20666480Read ↗

Comprehensive Proteomic Characterization of the Human Colorectal Carcinoma Reveals Signature Proteins and Perturbed PathwaysSemantic proximity Read ↗

Developing proteomics‐based biomarkers for colorectal neoplasms for clinical practice: Opportunities and challengesSemantic proximity Read ↗

Integrating proteomics and transcriptomics for the identification of potential targets in early colorectal cancerSemantic proximity Read ↗

Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal CancerSemantic proximity Read ↗

Ubiquitinomics revealed disease- and stage-specific patterns relevant for the 3PM approach in human sigmoid colon cancersSemantic proximity Read ↗

Dissecting characteristics and dynamics of differentially expressed proteins during multistage carcinogenesis of human colorectal cancerSemantic proximity Read ↗

Tissue Proteomic Signatures of BRAF-Mutated Colorectal Cancer Reveal New Insights into Aggressiveness, Immune Modulation, and Metabolic Reprogramming.Semantic proximity Read ↗

Identification of distinctive protein expression patterns in colorectal adenomaSemantic proximity Read ↗

Advancing In-Depth N-Terminomics Detection with a Cleavable 2-Pyridinecarboxyaldehyde ProbeSemantic proximity Read ↗

Pancreatic Ductal Adenocarcinoma Arising in Young and Old Patients Displays Similar Molecular FeaturesSemantic proximity Read ↗

Proteomics study of colorectal cancer and adenomatous polyps identifies TFR1, SAHH, and HV307 as potential biomarkers for screeningSemantic proximity Read ↗

Proteomic Profiling of Colon Cancer Tissues: Discovery of New Candidate BiomarkersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.