Article
CYP1A1, smoking and venous thromboembolism.
Thrombosis and haemostasis - 1 Oct 2010
Zhu Jin, Zheng Wen-Jie, Kong Fan-Cui, Zhang Wei-Juan, Wang He-Yao, Wang Chen
Abstract excerpt
Since CYP1A1 enzyme is involved in metabolism of tobacco carcinogens, the CYP1A1 gene may be of relevance to smoking-induced differences in the risks of venous thromboembolism (VTE). We conducted a case-control study to investigate genetic polymorphisms in CYP1A1 that might modify the risk of developing VTE. A total of 425 Chinese patients with VTE and 527 VTE-free control individuals, matched by age and gender,...
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