Article
Microfluidic bioassay to characterize parasitic nematode phenotype and anthelmintic resistance.
Parasitology - 1 Jan 2011
Chen Baozhen, Deutmeyer Alex, Carr John, Robertson Alan P, Martin Richard J, Pandey Santosh
Abstract excerpt
With increasing resistance to anti-parasitic drugs, it has become more important to detect and recognize phenotypes of resistant isolates. Molecular methods of detecting resistant isolates are limited at present. Here, we introduce a microfluidic bioassay to measure phenotype using parameters of nematode locomotion. We illustrate the technique on larvae of an animal parasite Oesophagostomum dentatum. Parameters...
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