Article
[Detection of ALK positive pulmonary adenocarcinoma using immunostaining].
Rinsho byori. The Japanese journal of clinical pathology - 1 Jun 2010
Ikeda Satoshi, Takabe Kazuhiko, Inagaki Masaharu, Funakoshi Naoya, Suzuki Keiko
Abstract excerpt
Although ALK-positive lung cancer cases have been recently reported, it is impossible to detect using only morphology technique. Furthermore, though RT-PCR and FISH techniques can be used for detection, they are not practical for screening. We investigated whether ALK-positive lung cancer could be detected using a conventional immunostaining method. Resected lung adenocarcinoma samples from 88 nonsmoker cases...
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