Article
Fat intake interacts with polymorphisms of Caspase9, FasLigand and PPARgamma apoptotic genes in modulating Crohn's disease activity.
Clinical nutrition (Edinburgh, Scotland) - 1 Dec 2010
Ferreira Paula, Cravo Marília, Guerreiro Catarina Sousa, Tavares Lourdes, Santos Paula Moura, Brito Miguel
Abstract excerpt
BACKGROUND & AIMS: Crohn's disease (CD) is a multifactorial disease where resistance to apoptosis is one major defect. Also, dietary fat intake has been shown to modulate disease activity. We aimed to explore the interaction between four single nucleotide polymorphisms (SNPs) in apoptotic genes and dietary fat intake in modulating disease activity in CD patients. METHODS: Polymerase Chain Reaction (PCR) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.