Article
BRAF in primary and recurrent papillary thyroid cancers: the relationship with (131)I and 2-[(18)F]fluoro-2-deoxy-D-glucose uptake ability.
European journal of endocrinology - 1 Oct 2010
Barollo Susi, Pennelli Gianmaria, Vianello Federica, Watutantrige Fernando Sara, Negro Isabella, Merante Boschin Isabella, Pelizzo Maria Rosa, Rugge Massimo, Mantero Franco, Nacamulli Davide, Girelli Maria Elisa, Busnardo Benedetto, Mian Caterina
Abstract excerpt
OBJECTIVE: BRAF V600E is a potential marker of poor prognosis in papillary thyroid cancers (PTC). In a previous report, we showed that recurrent PTC with no radioiodine ((131)I) uptake are frequently associated with BRAF mutations, a low expression of thyroid-related genes and a high expression of glucose type-1 transporter gene. AIM: The aim of the present study was to assess BRAF status in a large series of...
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