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Article

Two different phenotypes of fetuses with chromosomal triploidy: correlation with parental origin of the extra haploid set.

American journal of medical genetics - 15 Mar 1991

McFadden D E, Kalousek D K

Abstract excerpt

Triploidy is a condition in which there is over-representation of one parental genome. Recent work in experimental mouse embryo-genesis suggests that the parental origin of the extra genome in triploidy may have specific effects on both embryonic/fetal phenotype and placental development due to an "imprinting" effect. We studied 19 human triploid fetuses and discerned 2 distinct fetal phenotypes, as well as the...

Topics

Aneuploidy
Female
Fetus
Humans
Phenotype
Placenta
Pregnancy

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2063893
DOI: 10.1002/ajmg.1320380407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2063893-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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