Article
Correlation between the BRAF V600E mutation and tumor invasiveness in papillary thyroid carcinomas smaller than 20 millimeters: analysis of 1060 cases.
The Journal of clinical endocrinology and metabolism - 1 Sept 2010
Basolo Fulvio, Torregrossa Liborio, Giannini Riccardo, Miccoli Mario, Lupi Cristiana, Sensi Elisa, Berti Piero, Elisei Rossella, Vitti Paolo, Baggiani Angelo, Miccoli Paolo
Abstract excerpt
CONTEXT: Evaluation of the degree of neoplastic infiltration beyond the thyroid capsule remains a unique parameter that can be evaluated by histopathological examination to label a papillary thyroid carcinoma (PTC) of 20 mm or less in size as a pT1 or pT3 tumor. OBJECTIVE: We correlated the BRAF V600E mutation with both clinical-pathological features and the degree of neoplastic infiltration to redefine the...
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