Article
VirA: a virulence-related gene of Streptococcus suis serotype 2.
Microbial pathogenesis - 1 Nov 2010
Li Peng, Liu Jun, Zhu Lingwei, Qi Chong, Bei Weicheng, Cai Xuehui, Sun Yang, Feng Shuzhang
Abstract excerpt
Streptococcus suis serotype 2 is an important porcine and human zoonotic pathogen. Few virulence factors have been identified and the pathogenesis of infection is not fully understood. We have identified a novel virulence-related gene, virA, of S. suis 2. To investigate its role in pathogenesis, a virA deletion mutant of S. suis 2 wild-type strain ZY458, 458Deltavir, was constructed using suicide vector pSET4s,...
Topics
- Animals
- Bacterial Proteins
- Body Weight
- DNA, Bacterial
- Disease Models, Animal
- Gene Deletion
- Genetic Complementation Test
- Molecular Sequence Data
- Mutation
- Plasmids
- Rabbits
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Streptococcal Infections