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Article

Human uveal melanoma cells inhibit the immunostimulatory function of dendritic cells.

Experimental eye research - 1 Oct 2010

Ma Juan, Usui Yoshihiko, Takeuchi Masaru, Okunuki Yoko, Kezuka Takeshi, Zhang Lina, Mizota Atsushi, Goto Hiroshi

Abstract excerpt

Dendritic cells are critical for the induction of anti-tumor immunity. Recent studies suggest that some tumors may avoid immune destruction by inhibiting dendritic cell function. In this study, we investigated the effects of uveal melanoma on human dendritic cell phenotype and functions including surface antigen expression, cytokine production, and T cell activation. Dendritic cells were generated in the presence...

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Source

Identifiers

PMID: 20624388
DOI: 10.1016/j.exer.2010.06.025

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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