Article
Bikunin and α1-microglobulin/bikunin precursor (AMBP) gene mutational screening in patients with kidney stones: a case-control study.
Scandinavian journal of urology and nephrology - 1 Dec 2010
Igci Mehri, Arslan Ahmet, Igci Yusuf Ziya, Gogebakan Bulent, Erturhan M Sakip, Cengiz Beyhan, Oztuzcu Serdar, Cakmak Ecir Ali, Demiryurek A Tuncay
Abstract excerpt
OBJECTIVE: Bikunin is an inhibitor of kidney stone formation synthesized in the liver together with α(1)-microglobulin from the α(1)-microglobulin/bikunin precursor (AMBP) gene. The aim of this study was to investigate the possible association between bikunin/AMBP gene polymorphisms and urinary stone formation. MATERIAL AND METHODS: To analyse the DNA, blood samples were taken from 75 kidney stone formers who had...
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