Article
Inbreeding and nephrolithiasis in Croatian island isolates.
Collegium antropologicum - 1 Jun 2002
Rudan I, Padovan M, Rudan D, Campbell H, Biloglav Z, Janićjević B, Smolej-Narancić N, Rudan P
Abstract excerpt
The aim of this study was to investigate a recessive genetic component in susceptibility to nephrolithiasis (NL) by comparing its prevalence in highly inbred, moderately inbred and non-inbred villages of three Croatian islands: Brac, Hvar and Korcula. The average inbreeding coefficient of each village population (F) was estimated in a random sample of 20-30% adults from 14 villages using Wright's path method...
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