Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers.

Gastroenterology - 1 Dec 2010

Heald Brandie, Mester Jessica, Rybicki Lisa, Orloff Mohammed S, Burke Carol A, Eng Charis

Abstract excerpt

BACKGROUND & AIMS: Germline phosphatase and tensin homolog (PTEN) mutations cause Cowden syndrome (CS), associated with breast and thyroid cancers. Case reports found 35%-85% of CS patients had gastrointestinal (GI) hamartomas. The association of benign and malignant GI neoplasias with CS remains...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Colorectal Neoplasms
Share to Endoscopy, Gastrointestinal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Hamartoma Syndrome, Multiple

Share to Intestinal Polyps

Share to Point Mutation

Share to PTEN Phosphohydrolase

Source

Open in PubMed Open full text

Identifiers

PMID: 20600018
DOI: 10.1053/j.gastro.2010.06.061
PMCID: PMC3652614

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20600018-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers.PMID 20600018Read ↗

Upper and Lower Gastrointestinal Findings in PTEN Mutation–Positive Cowden Syndrome Patients Participating in an Active Surveillance ProgramSemantic proximity Read ↗

Gi Polyposis and Glycogenic Acanthosis of The Esophagus Associated With Pten Mutation Positive Cowden Syndrome in The Absence of Cutaneous ManifestationsSemantic proximity Read ↗

Colonic polyposis and neoplasia in Cowden syndrome.Semantic proximity Read ↗

Colorectal polyposis as a clue to the diagnosis of Cowden syndrome: Report of two cases and literature review.Semantic proximity Read ↗

Is colorectal surveillance indicated in patients with PTEN mutations?Semantic proximity Read ↗

Colorectal cancer risk in hamartomatous polyposis syndromesSemantic proximity Read ↗

A case of Cowden syndrome diagnosed from multiple gastric polyposis.Semantic proximity Read ↗

Hamartomatous polyposis syndromes.Semantic proximity Read ↗

Gastrointestinal polyposis and PTEN mutations: an under-acknowledged diagnostic criterionSemantic proximity Read ↗

PTEN hamartoma tumor syndromes.Semantic proximity Read ↗

First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity.Semantic proximity Read ↗

The Clinical Spectrum of PTEN MutationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.