Article
Association of -765G>C polymorphism of the COX-2 gene with recurrent embryo implantation failure in Southern Chilean women.
Clinica chimica acta; international journal of clinical chemistry - 11 Nov 2010
Salazar Luis A, Inostroza Mario, Jara Cristian, Vega Félix, García Ricardo, Ciuffardi Italo, Guzmán Neftalí
Abstract excerpt
BACKGROUND: Embryo implantation failure is considered an important cause of infertility in women undergoing assisted reproductive protocols. Recent studies demonstrated that the cyclooxygenase-2 (COX-2) enzyme is implicated in biosynthesis of prostaglandins and play an important role in the molecular implantation mechanisms. According to this evidence, we evaluated the potential association between the -765G>C...
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