Article
Neutrophil gelatinase-associated lipocalin immunoexpression in renal tumors: correlation with histotype and histological grade.
Oncology reports - 1 Aug 2010
Barresi Valeria, Ieni Antonio, Bolignano Davide, Magno Carlo, Buemi Michele, Barresi Gaetano
Abstract excerpt
Neutrophil gelatinase-associated lipocalin (NGAL) is a 25 kDa protein with roles in iron trafficking as well as in carcinogenesis and progression of several human neoplasias. Although the renal proximal tubule represents a major source of NGAL synthesis under various injurious stimuli to the kidney, NGAL expression has been rarely evaluated in renal tumors up to now. In view of this, in the present study we...
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