Article
Central nervous system serotonin and clustering of hostility, psychosocial, metabolic, and cardiovascular endophenotypes in men.
Psychosomatic medicine - 1 Sept 2010
Williams Redford B, Surwit Richard S, Siegler Ilene C, Ashley-Koch Allison E, Collins Ann L, Helms Michael J, Georgiades Anastasia, Boyle Stephen H, Brummett Beverly H, Barefoot John C, Grichnik Katherine, Stafford-Smith Mark, Suarez Edward C, Kuhn Cynthia M
Abstract excerpt
OBJECTIVE: To use measures of cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5HIAA) and genotype of a functional polymorphism of the monoamine oxidase A gene promoter (MAOA-uVNTR) to study the role of central nervous system (CNS) serotonin in clustering of hostility, other psychosocial, metabolic and cardiovascular endophenotypes. METHODS: In 86 healthy male volunteers, we evaluated CSF levels of the...
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