Article
New insights in collagen turnover in orofacial cleft patients.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jul 2010
Gagliano Nicoletta, Carinci Francesco, Moscheni Claudia, Torri Carlo, Pezzetti Furio, Scapoli Luca, Martinelli Marcella, Gioia Magda, Stabellini Giordano
Abstract excerpt
OBJECTIVE: We aimed to characterize the fibroblast phenotype of patients by analyzing gene and protein expression of cleft lip and/or cleft palate fibroblasts in relation to collagen turnover and extracellular matrix remodeling. PATIENTS: Human palatal fibroblasts were obtained from three healthy subjects without cleft lip and/or cleft palate and from three subjects with nonsyndromic cleft lip and/or cleft...
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