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Expression analysis of putative stem cell markers in human benign and malignant prostate

25 Jun 2010

Abstract excerpt

BACKGROUND: Stem cells were suggested to be present in human prostate cancer as a small population of distinct cells, which may contribute to carcinogenesis, tumor recurrence, and chemoresistance. To identify potential prostatic stem cells, we analyzed the expression of several potential stem cell markers in benign prostate and prostatic adenocarcinoma. METHODS: CD44, CD133, Oct4, SOX2, and EZH2 expression was...

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PMID: 20583131
DOI: 10.1002/pros.21217

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