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Article

Association between gap junction protein-alpha 8 polymorphisms and age-related cataract.

Molecular biology reports - 1 Feb 2011

Liu Yuanyuan, Ke Min, Yan Ming, Guo Shuren, Mothobi Mane Emily, Chen Qiang, Zheng Fang

Abstract excerpt

GJA8 plays an important role in lens growth and transparency. Therefore, we hypothesized that two single nucleotide polymorphisms (SNPs) in GJA8 might be associated with age-related cataract. We investigated the SNPs rs1495960 and rs9437983 using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and DNA sequencing, in 96 age-related cataract patients, and 208 gender- and age-matched...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20582632
DOI: 10.1007/s11033-010-0230-z

Genes

GJA8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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