Article
The use of arrays in preimplantation genetic diagnosis and screening.
Fertility and sterility - 1 Sept 2010
Harper Joyce C, Harton Gary
Abstract excerpt
BACKGROUND: In preimplantation genetic diagnosis (PGD), polymerase chain reaction has been used to detect monogenic disorders, and in PGD/preimplantation genetic screening (PGS), fluorescence in situ hybridization (FISH) has been used to analyze chromosomes. Ten randomized controlled trials (RCTs) using FISH-based PGS on cleavage-stage embryos and one on blastocyst-stage embryos have shown that PGS does not...
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