Article
An update of preimplantation genetic diagnosis in gene diseases, chromosomal translocation, and aneuploidy screening
1 Jan 2011
Abstract excerpt
Preimplantation genetic diagnosis (PGD) is gradually widely used in prevention of gene diseases and chromosomal abnormalities. Much improvement has been achieved in biopsy technique and molecular diagnosis. Blastocyst biopsy can increase diagnostic accuracy and reduce allele dropout. It is cost-effective and currently plays an important role. Whole genome amplification permits subsequent individual detection of...