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Article

Genetic association of NALP1 with generalized vitiligo in Jordanian Arabs.

Archives of dermatological research - 1 Oct 2010

Alkhateeb Asem, Qarqaz Firas

Abstract excerpt

Generalized vitiligo is an autoimmune disorder characterized by patchy loss of pigmentation due to autoimmune destruction of melanocytes in the involved areas. Vitiligo is a polygenic, multifactorial disorder involving multiple genes and unknown environmental triggers. Recently, genetic variation in NALP1 (also called NLRP1), encoding a key regulator of the innate immune response, has been associated with...

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Source

Identifiers

PMID: 20574744
DOI: 10.1007/s00403-010-1064-1

Genes

NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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