Article
Parvovirus B19 genotype specific amino acid substitution in NS1 reduces the protein's cytotoxicity in culture.
International journal of medical sciences - 25 May 2010
Kivovich Violetta, Gilbert Leona, Vuento Matti, Naides Stanley J
Abstract excerpt
A clinical association between idiopathic liver disease and parvovirus B19 infection has been observed. Fulminant liver failure, not associated with other liver-tropic viruses, has been attributed to B19 in numerous reports, suggesting a possible role for B19 components in the extensive hepatocyte cytotoxicity observed in this condition. A recent report by Abe and colleagues (Int J Med Sci. 2007;4:105-9)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
