Article
Sarcoidosis and major histocompatibility complex genes with special emphasis on BF F subtypes.
Complement and inflammation - 1 Jan 1991
Finco O, Martinetti M, Dondi E, Luisetti M, Pasturenzi L, Cuccia M
Abstract excerpt
Frequencies for HLA class I and II histoglobulins and C4A, C4B, BF complement proteins were performed for 59 sarcoidosis patients. The DR5 allele was present in 55.9% of patients as compared to 31.5% of controls. We noticed that its increase was more relevant in males and in those with a poor prognosis. BF F allele was significantly over-represented in patients (29.09% vs. 19.15% of control), especially in women....
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