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Article

Mutational analysis of HOXA2 and SIX2 in a Bronx population with isolated microtia.

International journal of pediatric otorhinolaryngology - 1 Aug 2010

Monks Dennis C, Jahangir Arthee, Shanske Alan L, Samanich Joy, Morrow Bernice E, Babcock Melanie

Abstract excerpt

OBJECTIVE: Microtia is a developmental malformation of the external ear with genetic and environmental causes. The prevalence of microtia varies but several studies suggest increased incidence in Hispanic and African American populations. No causal genetic mutations have been identified in these populations. Mutations in the homeobox gene HOXA2 caused microtia in a single Iranian family. Another homeobox gene,...

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Source

Identifiers

PMID: 20542577
DOI: 10.1016/j.ijporl.2010.05.004

Genes

HOXA2
SIX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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