Article
Unusual organization, complexity and redundancy at the Escherichia coli hcp-hcr operon promoter.
The Biochemical journal - 15 Aug 2010
Chismon David L, Browning Douglas F, Farrant Gregory K, Busby Stephen J W
Abstract excerpt
Expression from the Escherichia coli hcp-hcr operon promoter is optimally induced during anaerobic conditions in the presence of nitrite. This expression depends on transcription activation by FNR (fumarate and nitrate reduction regulator), which binds to a target centred at position -72.5 upstream of the transcript start site. Mutational analysis was exploited to identify the corresponding -10 and -35 hexamer...
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