Article
Non-specific protein modifications by a phytochemical induce heat shock response for self-defense.
PloS one - 1 Jan 2013
Ohnishi Kohta, Ohkura Shinya, Nakahata Erina, Ishisaka Akari, Kawai Yoshichika, Terao Junji, Mori Taiki, Ishii Takeshi, Nakayama Tsutomu, Kioka Noriyuki, Matsumoto Shinya, Ikeda Yasutaka, Akiyama Minoru, Irie Kazuhiro, Murakami Akira
Abstract excerpt
Accumulated evidence shows that some phytochemicals provide beneficial effects for human health. Recently, a number of mechanistic studies have revealed that direct interactions between phytochemicals and functional proteins play significant roles in exhibiting their bioactivities. However, their binding selectivities to biological molecules are considered to be lower due to their small and simple structures. In...
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