Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem Cells

8 Jun 2010

Abstract excerpt

Human embryonic stem cells (hESC) present a novel platform for in vitro investigation of the early embryonic cellular response to ionizing radiation. Thus far, no study has analyzed the genome-wide transcriptional response to ionizing radiation in hESCs, nor has any study assessed their ability to form teratomas, the definitive test of pluripotency. In this study, we use microarrays to analyze the global gene...

Topics

Join the communities discussing this publication.

Cancer Cells and Metastasis
Pluripotent Stem Cells Research
Renal and related cancers

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20530673
DOI: 10.1158/0008-5472.can-09-4238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem CellsPMID 20530673Read ↗

Lessons Learned about Human Stem Cell Responses to Ionizing Radiation Exposures: A Long Road Still Ahead of UsSemantic proximity Read ↗

Responses of human embryonic stem cells and their differentiated progeny to ionizing radiationSemantic proximity Read ↗

Expression of pluripotency-associated genes in the surviving fraction of cultured human embryonic stem cells is not significantly affected by ionizing radiationSemantic proximity Read ↗

Concise Review: The Effect of Low-Dose Ionizing Radiation on Stem Cell Biology: A Contribution to Radiation RiskSemantic proximity Read ↗

Low-Dose Radiation Can Cause Epigenetic Alterations Associated With Impairments in Both Male and Female Reproductive CellsSemantic proximity Read ↗

Identification of Differential Gene Expression Patterns after Acute Exposure to High and Low Doses of Low-LET Ionizing Radiation in a Reconstituted Human Skin TissueSemantic proximity Read ↗

Ionizing Radiation Induces Stemness in Cancer CellsSemantic proximity Read ↗

Molecular and epigenetic regulatory mechanisms of normal stem cell radiosensitivitySemantic proximity Read ↗

Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice.Semantic proximity Read ↗

Molecular Pathogenesis of Radiation-Induced Cell Toxicity in Stem CellsSemantic proximity Read ↗

Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state.Semantic proximity Read ↗

Radiation‐Induced Reprogramming of Breast Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.