Article
Phylodynamic analyses of rotavirus genotypes G9 and G12 underscore their potential for swift global spread.
Molecular biology and evolution - 1 Oct 2010
Matthijnssens Jelle, Heylen Elisabeth, Zeller Mark, Rahman Mustafizur, Lemey Philippe, Van Ranst Marc
Abstract excerpt
Rotaviruses (RVs) are responsible for more than 600,000 child deaths each year. The worldwide introduction of two life oral vaccines RotaTeq and Rotarix is believed to reduce this number significantly. Before the licensing of both vaccines, two new genotypes, G9 and G12, emerged in the human population and were able to spread across the entire globe in a very short time span. To quantify the VP7 mutation rates of...
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